Today 3Dconnexion announce a new product called SpaceMouse Pro. The product fits in the same class of 3D mouse as the SpaceExplorer with some added improvements in ergonomics. The hand rest is full size and soft coated for comfort. The buttons for zoom have been rearranged and the keyboard keys for Esc, Shift, Enter and Ctrl have been made larger and at an easier reach to the hand on the 3D mouse. This should make it so you don’t have to use the keyboard as often with your left hand.
There are four buttons on the top are context sensitive to the open program (although I’m hoping they can be context sensitive to objects in Civil 3D). It also puts what the numbers do up on the monitor, so you know what each button does without looking down at the mouse. This lets you keep your eyes on the monitor while you design. The mouse still has the 3D Navigation with six degree of freedoms to allow easy navigation through a model. Another added benefit is new drivers with a virtual number pad. This allows you to keep your hands on your mice and enter numbers using the regular mouse.
For more information take a look at their website http://www.3dconnexion.com/products/spacemousepro.html, if you are at Autodesk University this year stop by their booth to test drive it in person.